Yea, you can but unless you plan to leave your PC on all the time and open ports on your firewall directly to your PC.

There are some major risks on doing that though.

You can host an instance on any pc you can install stuff on or run docker containers on.

The issue, as the other commenter said, is that the computer needs to run so that it can catch and send federated stuff. Otherwise you are an island which can be a good usecase for a school or small company but not generally.

A probable usecase would be an old pc which you leave running or a raspberry pi. You route the federation ports through your router and nothing else. That way you have full federation and very few attack vectors. The most secure way to use it is locally on your network or by connecting via vpn.

What do you mean by PC? Just asking because sometimes people use PC to refer to a computer that runs Windows. Just sort of how the vernacular ended up going over the years.

I can’t help, but even with Windows I think they have a way to run Linux stuff on it now, so it should be possible.